Expand this Topic clickable element to expand a topic
Skip to content
Optica Publishing Group

Multiharmonic-generation biopsy of skin

Not Accessible

Your library or personal account may give you access

Abstract

Because it avoids the in-focus photodamage and phototoxicity problem of two-photon-fluorescence excitation, multiharmonic-generation biopsy based on a 1200–1300-nm light source could provide a truly noninvasive and highly penetrative optical sectioning of skin. We study multiharmonic-generation biopsy of fixed mouse skin. Our preliminary study suggests that this technique could provide submicrometer-resolution deep-tissue noninvasive biopsy images in skin without the use of fluorescence and exogenous markers.

© 2003 Optical Society of America

Full Article  |  PDF Article
More Like This
Optical biopsy of fixed human skin with backward-collected optical harmonics signals

Shih-Peng Tai, Tsung-Han Tsai, Wen-Jeng Lee, Dar-Bin Shieh, Yi-Hua Liao, Hsin-Yi Huang, Kenneth Y.-J. Zhang, Hsiang-Lin Liu, and Chi-Kuang Sun
Opt. Express 13(20) 8231-8242 (2005)

Quantitative analysis of intrinsic skin aging in dermal papillae by in vivo harmonic generation microscopy

Yi-Hua Liao, Wei-Cheng Kuo, Sin-Yo Chou, Cheng-Shiun Tsai, Guan-Liang Lin, Ming-Rung Tsai, Yuan-Ta Shih, Gwo-Giun Lee, and Chi-Kuang Sun
Biomed. Opt. Express 5(9) 3266-3279 (2014)

In vivo developmental biology study using noninvasive multi-harmonic generation microscopy

Shi-Wei Chu, Szu-Yu Chen, Tsung-Han Tsai, Tzu-Ming Liu, Cheng-Yung Lin, Huai-Jen Tsai, and Chi-Kuang Sun
Opt. Express 11(23) 3093-3099 (2003)

Cited By

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Figures (3)

You do not have subscription access to this journal. Figure files are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Select as filters


Select Topics Cancel
© Copyright 2024 | Optica Publishing Group. All Rights Reserved