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Real-time measurement of in vitro flow by Fourier-domain color Doppler optical coherence tomography

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Abstract

The possibility of measuring a full Doppler flow depth profile in parallel by use of frequency-domain optical coherence tomography is demonstrated. The method is based on a local phase analysis of the backscattered signal and allows for imaging of bidirectional Doppler flow. The Doppler frequency limit is 5 kHz for the presented measurements and is set by half of the frame rate of the CCD detector array. We measured the flow of 0.3µm microspheres suspended in distilled water at controlled flow rates and in vitro human blood flow through a 200µm capillary with a real-time color-encoded Doppler tomogram rate of 2–3/s.

© 2004 Optical Society of America

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