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Pulsed near-infrared laser diode excitation system for biomedical photoacoustic imaging

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Abstract

A pulsed laser diode system operating at 905nm has been developed for the generation of photoacoustic signals in tissue. It was evaluated by measuring the photoacoustic waveforms generated in a blood vessel phantom comprising three dye-filled (μa=1mm1) tubes of diameters 120580μm immersed to a maximum depth of 9mm in a turbid liquid (μs=1mm1). The system was then combined with a cylindrical scanning system to obtain two-dimensional images of a tissue phantom. The signal-to-noise ratio of the detected signals in both cases and the image contrast in the latter suggest that such a system could provide a compact and inexpensive alternative to current excitation sources for superficial imaging applilcations.

© 2006 Optical Society of America

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