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Printed optics: phantoms for quantitative deep tissue fluorescence imaging

Abstract

Three-dimensional (3D) printing allows for complex or physiologically realistic phantoms, useful, for example, in developing biomedical imaging methods and for calibrating measured data. However, available 3D printing materials provide a limited range of static optical properties. We overcome this limitation with a new method using stereolithography that allows tuning of the printed phantom’s optical properties to match that of target tissues, accomplished by printing a mixture of polystyrene microspheres and clear photopolymer resin. We show that Mie theory can be used to design the optical properties, and demonstrate the method by fabricating a mouse phantom and imaging it using fluorescence optical diffusion tomography.

© 2016 Optical Society of America

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Corrections

Brian Z. Bentz, Anna G. Bowen, Dergan Lin, Daniel Ysselstein, Davin H. Huston, Jean-Christophe Rochet, and Kevin J. Webb, "Printed optics: phantoms for quantitative deep tissue fluorescence imaging: publisher’s note," Opt. Lett. 41, 5575-5575 (2016)
https://opg.optica.org/ol/abstract.cfm?uri=ol-41-23-5575

17 November 2016: Corrections were made to page 5230 and to page 5231.


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