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Image reversal reactive immersion lithography improves the detection limit of focal molography

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Abstract

Focal molography is a label-free optical biosensing method that relies on a coherent pattern of binding sites for biomolecular interaction analysis. Reactive immersion lithography (RIL) is central to the patterning of molographic chips but has potential for improvements. Here, we show that applying the idea of image reversal to RIL enables the fabrication of coherent binding patterns of increased quality (i.e., higher analyte efficiency). Thereby the detection limit of focal molography in biological assays can be improved.

© 2018 Optical Society of America

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Corrections

Andreas Frutiger, Cla Duri Tschannen, Yves Blickenstorfer, Andreas M. Reichmuth, Christof Fatttinger, and Janos Vörös, "Image reversal reactive immersion lithography improves the detection limit of focal molography: erratum," Opt. Lett. 45, 918-918 (2020)
https://opg.optica.org/ol/abstract.cfm?uri=ol-45-4-918

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